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Kidney Transplant in India

What is Kidney Transplant ?

Kidney transplantation or renal transplantation is the organ transplant of a kidney into a patient with end-stage renal disease. Kidney transplantation is typically classified as deceased-donor (formerly known as cadaveric) or living-donor transplantation depending on the source of the donor organ. Living-donor renal transplants are further characterized as genetically related (living-related) or non-related (living-unrelated) transplants, depending on whether a biological relationship exists between the donor and recipient. Exchanges and chains are a novel approach to expand the living donor pool.

Sources of kidneys

Since medication to prevent rejection is so effective, donors do not need to be similar to their recipient. Most donated kidneys come from deceased donors; however, the utilization of living donors in the United States is on the rise. In 2006, 47% of donated kidneys were from living donors.This varies by country: for example, only 3% of kidneys transplanted during 2006 in Spain came from living donors.

Living donors

Potential donors are carefully evaluated on medical and psychological grounds. This ensures that the donor is fit for surgery and has no disease which brings undue risk or likelihood of a poor outcome for either the donor or recipient. The psychological assessment is to ensure the donor gives informed consent and is not coerced. In countries where paying for organs is illegal, the authorities may also seek to ensure that a donation has not resulted from a financial transaction.

Prognosis

Kidney transplantation is a life-extending procedure.The typical patient will live 10 to 15 years longer with a kidney transplant than if kept on dialysis.The increase in longevity is greater for younger patients, but even 75-year-old recipients (the oldest group for which there is data) gain an average four more years of life. People generally have more energy, a less restricted diet, and fewer complications with a kidney transplant than if they stay on conventional dialysis.

Kidney Transplant


Complications

Problems after a transplant may include: Post operative complication, bleeding, infection, vascular thrombosis and urinary complications

  • Transplant rejection (hyperacute, acute or chronic)
  • Infections and sepsis due to the immunosuppressant drugs that are required to decrease risk of rejection
  • Post-transplant lymphoproliferative disorder (a form of lymphoma due to the immune suppressants)
  • Imbalances in electrolytes including calcium and phosphate which can lead to bone problems among other things
  • Other side effects of medications including gastrointestinal inflammation and ulceration of the stomach and esophagus, hirsutism (excessive hair growth in a male-pattern distribution), hair loss, obesity, acne, diabetes mellitus type 2, hypercholesterolemia, and osteoporosis.
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